Publications
2024
Zhang F, Schmidt F, Muecksch F, Wang Z, Gazumyan A, Nussenzweig MC, Gaebler C, Caskey M, Hatziioannou T, Bieniasz PD. 2024. ‘SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity’, mBio, 15. Article
Sankhala RS, Lal KG, Jensen JL, Dussupt V, Mendez-Rivera L, Bai H, Wieczorek L, Mayer SV, Zemil M, Wagner DA, Townsley SM, Hajduczki A, Chang WC, Chen WH, Donofrio GC, Jian N, King HAD, Lorang CG, Martinez EJ, Rees PA, Peterson CE, Schmidt F, Hart TJ, Duso DK, Kummer LW, Casey SP, Williams JK, Kannan S, Slike BM, Smith L, Swafford I, Thomas PV, Tran U, Currier JR, Bolton DL, Davidson E, Doranz BJ, Hatziioannou T, Bieniasz PD, Paquin-Proulx D, Reiley WW, Rolland M, Sullivan NJ, Vasan S, Collins ND, Modjarrad K, Gromowski GD, Polonis VR, Michael NL, Krebs SJ, Joyce MG. 2024. ‘Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques’, Nature Communications, 15. Article
2023
T. Zang, E. Osei Kuffour, V. A. Baharani, M. Canis, F. Schmidt, J. Da Silva, A. Lercher, P. Chaudhary, H. Hoffmann, A. Gazumyan, I. C. Miranda, M. R. MacDonald, C. M. Rice, M. C. Nussenzweig, T. Hatziioannou, P. D. Bieniasz. 2023. ‘Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies’, PNAS, 120. Article
Lei, X., D. Goncalves-Carneiro, T. M. Zang, and P. D. Bieniasz. 2023. 'Initiation of HIV-1 Gag lattice assembly is required for recognition of the viral genome packaging signal', Elife, 12. Article
Murphy, E. A., C. Guzman-Cardozo, A. C. Sukhu, D. J. Parks, M. Prabhu, I. Mohammed, M. Jurkiewicz, T. J. Ketas, S. Singh, M. Canis, E. Bednarski, A. Hollingsworth, E. M. Thompson, D. Eng, P. D. Bieniasz, L. E. Riley, T. Hatziioannou, and Y. J. Yang. 2023. 'SARS-CoV-2 vaccination, booster, and infection in pregnant population enhances passive immunity in neonates', Nat Commun, 14: 4598. Article
Nangarlia, A., F. F. Hassen, G. Canziani, P. Bandi, C. Talukder, F. Zhang, D. Krauth, E. N. Gary, D. B. Weiner, P. Bieniasz, S. Navas-Martin, B. R. O'Keefe, C. G. Ang, and I. Chaiken. 2023. 'Irreversible Inactivation of SARS-CoV-2 by Lectin Engagement with Two Glycan Clusters on the Spike Protein', Biochemistry, 62: 2115-27. Article
Schaefer-Babajew, D., Z. Wang, F. Muecksch, A. Cho, M. Loewe, M. Cipolla, R. Raspe, B. Johnson, M. Canis, J. DaSilva, V. Ramos, M. Turroja, K. G. Millard, F. Schmidt, L. Witte, J. Dizon, I. Shimeliovich, K. H. Yao, T. Y. Oliveira, A. Gazumyan, C. Gaebler, P. D. Bieniasz, T. Hatziioannou, M. Caskey, and M. C. Nussenzweig. 2023. 'Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination', Nature, 613: 735-42. Article
Schiepers, A., M. F. L. van 't Wout, A. J. Greaney, T. Zang, H. Muramatsu, P. J. C. Lin, Y. K. Tam, L. Mesin, T. N. Starr, P. D. Bieniasz, N. Pardi, J. D. Bloom, and G. D. Victora. 2023. 'Molecular fate-mapping of serum antibody responses to repeat immunization', Nature, 615: 482-89. Article
Swanstrom, A. E., R. J. Gorelick, J. L. Welker, F. Schmidt, B. Lu, K. Wang, W. Rowe, M. W. Breed, K. E. Killoran, J. A. Kramer, D. Donohue, J. D. Roser, P. D. Bieniasz, T. Hatziioannou, C. Pyle, J. A. Thomas, C. M. Trubey, J. Zheng, W. Blair, S. R. Yant, J. D. Lifson, and G. Q. Del Prete. 2023. 'Long-acting lenacapavir protects macaques against intravenous challenge with simian-tropic HIV', EBioMedicine, 95: 104764. Article
Witte, L., V. A. Baharani, F. Schmidt, Z. Wang, A. Cho, R. Raspe, C. Guzman-Cardozo, F. Muecksch, M. Canis, D. J. Park, C. Gaebler, M. Caskey, M. C. Nussenzweig, T. Hatziioannou, and P. D. Bieniasz. 2023. 'Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape', Nat Commun, 14: 302. Article
Yang, L., M. Van Beek, Z. Wang, F. Muecksch, M. Canis, T. Hatziioannou, P. D. Bieniasz, M. C. Nussenzweig, and A. K. Chakraborty. 2023. 'Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain', Cell Rep, 42: 112256. Article
Zhang, F., J. Jenkins, R. V. H. de Carvalho, S. Nakandakari-Higa, T. Chen, M. E. Abernathy, V. A. Baharani, E. K. Nyakatura, D. Andrew, I. V. Lebedeva, I. C. Lorenz, H. H. Hoffmann, C. M. Rice, G. D. Victora, C. O. Barnes, T. Hatziioannou, and P. D. Bieniasz. 2023. 'Pan-sarbecovirus prophylaxis with human anti-ACE2 monoclonal antibodies', Nat Microbiol, 8: 1051-63. Article
2022
Bednarski, E., P. M. Del Rio Estrada, J. DaSilva, C. Boukadida, F. Zhang, Y. A. Luna-Villalobos, X. Rodriguez-Rangel, E. Piten-Isidro, E. Luna-Garcia, D. Diaz Rivera, D. M. Lopez-Sanchez, D. Tapia-Trejo, M. Soto-Nava, M. Astorga-Castaneda, J. O. Martinez-Moreno, G. S. Urbina-Granados, J. A. Jimenez-Jacinto, F. J. Serna Alvarado, Y. E. Enriquez-Lopez, O. Lopez-Arellano, G. Reyes-Teran, P. D. Bieniasz, S. Avila-Rios, and T. Hatziioannou. 2022. 'Antibody and Memory B-Cell Immunity in a Heterogeneously SARS-CoV-2-Infected and -Vaccinated Population', mBio, 13: e0084022. Article
Brown, J. A., K. Z. Sanidad, S. Lucotti, C. M. Lieber, R. M. Cox, A. Ananthanarayanan, S. Basu, J. Chen, M. Shan, M. Amir, F. Schmidt, Y. Weisblum, M. Cioffi, T. Li, F. M. Rowdo, M. L. Martin, C. J. Guo, C. Lyssiotis, B. T. Layden, A. J. Dannenberg, P. D. Bieniasz, B. Lee, N. Inohara, I. Matei, R. K. Plemper, and M. Y. Zeng. 2022. 'Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection', Gut Microbes, 14: 2105609. Article
Gaebler, C., J. DaSilva, E. Bednarski, F. Muecksch, F. Schmidt, Y. Weisblum, K. G. Millard, M. Turroja, A. Cho, Z. Wang, M. Caskey, M. C. Nussenzweig, P. D. Bieniasz, and T. Hatziioannou. 2022. 'Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization After Messenger RNA Vaccination and Variant Breakthrough Infection', Open Forum Infect Dis, 9: ofac227. Article
Goncalves-Carneiro, D., E. Mastrocola, X. Lei, J. DaSilva, Y. F. Chan, and P. D. Bieniasz. 2022. 'Rational attenuation of RNA viruses with zinc finger antiviral protein', Nat Microbiol, 7: 1558-67. Article
Mair, M. J., A. Leibetseder, G. Heller, R. Puhr, E. Tomasich, S. Goldberger, T. Hatziioannou, A. Wohrer, G. Widhalm, K. Dieckmann, M. Aichholzer, S. Weis, T. von Oertzen, J. Furtner, J. Pichler, M. Preusser, and A. S. Berghoff. 2022. 'Early Postoperative Treatment versus Initial Observation in CNS WHO Grade 2 and 3 Oligodendroglioma: Clinical Outcomes and DNA Methylation Patterns', Clin Cancer Res, 28: 4565-73. Article
McCance, K., H. Wise, J. Simpson, B. Batchelor, H. Hale, L. McDonald, A. Zorzoli, E. Furrie, C. Chopra, F. Muecksch, T. Hatziioannou, P. D. Bieniasz, K. Templeton, and S. Jenks. 2022. 'Evaluation of SARS-CoV-2 antibody point of care devices in the laboratory and clinical setting', PLoS One, 17: e0266086. Article
Muecksch, F., Z. Wang, A. Cho, C. Gaebler, T. Ben Tanfous, J. DaSilva, E. Bednarski, V. Ramos, S. Zong, B. Johnson, R. Raspe, D. Schaefer-Babajew, I. Shimeliovich, M. Daga, K. H. Yao, F. Schmidt, K. G. Millard, M. Turroja, M. Jankovic, T. Y. Oliveira, A. Gazumyan, M. Caskey, T. Hatziioannou, P. D. Bieniasz, and M. C. Nussenzweig. 2022. 'Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost', Nature, 607: 128-34. Article
Muecksch, F., H. Wise, K. Templeton, B. Batchelor, M. Squires, K. McCance, L. Jarvis, K. Malloy, E. Furrie, C. Richardson, J. MacGuire, I. Godber, A. Burns, S. Mavin, F. Zhang, F. Schmidt, P. D. Bieniasz, S. Jenks, and T. Hatziioannou. 2022. 'Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: a serological analysis', Lancet Microbe, 3: e493-e502. Article
Schmidt, F., F. Muecksch, Y. Weisblum, J. Da Silva, E. Bednarski, A. Cho, Z. Wang, C. Gaebler, M. Caskey, M. C. Nussenzweig, T. Hatziioannou, and P. D. Bieniasz. 2022. 'Plasma Neutralization of the SARS-CoV-2 Omicron Variant', N Engl J Med, 386: 599-601. Article
Starzer, A. M., G. Heller, E. Tomasich, T. Melchardt, K. Feldmann, T. Hatziioannou, S. Traint, C. Minichsdorfer, U. Schwarz-Nemec, M. Nackenhorst, L. Mullauer, M. Preusser, A. S. Berghoff, and T. Fuereder. 2022. 'DNA methylation profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck squamous cell carcinoma', J Immunother Cancer, 10. Article
Wang, Z., F. Muecksch, A. Cho, C. Gaebler, H. H. Hoffmann, V. Ramos, S. Zong, M. Cipolla, B. Johnson, F. Schmidt, J. DaSilva, E. Bednarski, T. Ben Tanfous, R. Raspe, K. Yao, Y. E. Lee, T. Chen, M. Turroja, K. G. Milard, J. Dizon, A. Kaczynska, A. Gazumyan, T. Y. Oliveira, C. M. Rice, M. Caskey, P. D. Bieniasz, T. Hatziioannou, C. O. Barnes, and M. C. Nussenzweig. 2022. 'Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins', Immunity, 55: 998-1012 e8. Article
Xue, G., K. Braczyk, D. Goncalves-Carneiro, D. M. Dawidziak, K. Sanchez, H. Ong, Y. Wan, K. K. Zadrozny, B. K. Ganser-Pornillos, P. D. Bieniasz, and O. Pornillos. 2022. 'Poly(ADP-ribose) potentiates ZAP antiviral activity', PLoS Pathog, 18: e1009202. Article
Zhang, F., T. M. Zang, E. M. Stevenson, X. Lei, D. C. Copertino, T. M. Mota, J. Boucau, W. F. Garcia-Beltran, R. B. Jones, and P. D. Bieniasz. 2022. 'Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins', Proc Natl Acad Sci U S A, 119: e2209042119. Article
2021
Bou-Nader, C., F. Muecksch, J. B. Brown, J. M. Gordon, A. York, C. Peng, R. Ghirlando, M. F. Summers, P. D. Bieniasz, and J. Zhang. 2021. 'HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization', Cell Host Microbe, 29: 1421-36 e7. Article
Cho, A., F. Muecksch, D. Schaefer-Babajew, Z. Wang, S. Finkin, C. Gaebler, V. Ramos, M. Cipolla, P. Mendoza, M. Agudelo, E. Bednarski, J. DaSilva, I. Shimeliovich, J. Dizon, M. Daga, K. G. Millard, M. Turroja, F. Schmidt, F. Zhang, T. B. Tanfous, M. Jankovic, T. Y. Oliveria, A. Gazumyan, M. Caskey, P. D. Bieniasz, T. Hatziioannou, and M. C. Nussenzweig. 2021. 'Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination', Nature, 600: 517-22. Article
Coffin, J., J. Blomberg, H. Fan, R. Gifford, T. Hatziioannou, D. Lindemann, J. Mayer, J. Stoye, M. Tristem, W. Johnson, and Consortium Ictv Report. 2021. 'ICTV Virus Taxonomy Profile: Retroviridae 2021', J Gen Virol, 102. Article
De Gasparo, R., M. Pedotti, L. Simonelli, P. Nickl, F. Muecksch, I. Cassaniti, E. Percivalle, J. C. C. Lorenzi, F. Mazzola, D. Magri, T. Michalcikova, J. Haviernik, V. Honig, B. Mrazkova, N. Polakova, A. Fortova, J. Tureckova, V. Iatsiuk, S. Di Girolamo, M. Palus, D. Zudova, P. Bednar, I. Bukova, F. Bianchini, D. Mehn, R. Nencka, P. Strakova, O. Pavlis, J. Rozman, S. Gioria, J. C. Sammartino, F. Giardina, S. Gaiarsa, Q. Pan-Hammarstrom, C. O. Barnes, P. J. Bjorkman, L. Calzolai, A. Piralla, F. Baldanti, M. C. Nussenzweig, P. D. Bieniasz, T. Hatziioannou, J. Prochazka, R. Sedlacek, D. F. Robbiani, D. Ruzek, and L. Varani. 2021a. 'Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice', Nature, 597: E2. Article
Dussupt, V., R. S. Sankhala, L. Mendez-Rivera, S. M. Townsley, F. Schmidt, L. Wieczorek, K. G. Lal, G. C. Donofrio, U. Tran, N. D. Jackson, W. I. Zaky, M. Zemil, S. R. Tritsch, W. H. Chen, E. J. Martinez, A. Ahmed, M. Choe, W. C. Chang, A. Hajduczki, N. Jian, C. E. Peterson, P. A. Rees, M. Rutkowska, B. M. Slike, C. N. Selverian, I. Swafford, I. T. Teng, P. V. Thomas, T. Zhou, C. J. Smith, J. R. Currier, P. D. Kwong, M. Rolland, E. Davidson, B. J. Doranz, C. N. Mores, T. Hatziioannou, W. W. Reiley, P. D. Bieniasz, D. Paquin-Proulx, G. D. Gromowski, V. R. Polonis, N. L. Michael, K. Modjarrad, M. G. Joyce, and S. J. Krebs. 2021. 'Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations', Nat Immunol, 22: 1503-14. Article
Goncalves-Carneiro, D., M. A. Takata, H. Ong, A. Shilton, and P. D. Bieniasz. 2021. 'Origin and evolution of the zinc finger antiviral protein', PLoS Pathog, 17: e1009545. Article
Greaney, A. J., T. N. Starr, C. O. Barnes, Y. Weisblum, F. Schmidt, M. Caskey, C. Gaebler, A. Cho, M. Agudelo, S. Finkin, Z. Wang, D. Poston, F. Muecksch, T. Hatziioannou, P. D. Bieniasz, D. F. Robbiani, M. C. Nussenzweig, P. J. Bjorkman, and J. D. Bloom. 2021. 'Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies', Nat Commun, 12: 4196. Article
Hacisuleyman, E., C. Hale, Y. Saito, N. E. Blachere, M. Bergh, E. G. Conlon, D. J. Schaefer-Babajew, J. DaSilva, F. Muecksch, C. Gaebler, R. Lifton, M. C. Nussenzweig, T. Hatziioannou, P. D. Bieniasz, and R. B. Darnell. 2021. 'Vaccine Breakthrough Infections with SARS-CoV-2 Variants', N Engl J Med, 384: 2212-18. Article
Honjo, K., R. M. Russell, R. Li, W. Liu, R. Stoltz, E. M. Tabengwa, Y. Hua, L. Prichard, A. N. Kornbrust, S. Sterrett, M. B. Marques, J. L. Lima, C. M. Lough, T. P. McCarty, T. J. Ketas, T. Hatziioannou, P. D. Bieniasz, D. T. Redden, J. P. Moore, P. A. Goepfert, S. L. Heath, B. H. Hahn, and R. S. Davis. 2021. 'Convalescent plasma-mediated resolution of COVID-19 in a patient with humoral immunodeficiency', Cell Rep Med, 2: 100164. Article
Jette, C. A., A. A. Cohen, P. N. P. Gnanapragasam, F. Muecksch, Y. E. Lee, K. E. Huey-Tubman, F. Schmidt, T. Hatziioannou, P. D. Bieniasz, M. C. Nussenzweig, A. P. West, Jr., J. R. Keeffe, P. J. Bjorkman, and C. O. Barnes. 2021. 'Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies', Cell Rep, 36: 109760. Article
Liu, W., R. M. Russell, F. Bibollet-Ruche, A. N. Skelly, S. Sherrill-Mix, D. A. Freeman, R. Stoltz, E. Lindemuth, F. H. Lee, S. Sterrett, K. J. Bar, N. Erdmann, S. Gouma, S. E. Hensley, T. Ketas, A. Cupo, V. M. Cruz Portillo, J. P. Moore, P. D. Bieniasz, T. Hatziioannou, G. Massey, M. B. Minyard, M. S. Saag, R. S. Davis, G. M. Shaw, W. J. Britt, S. M. Leal, Jr., P. Goepfert, and B. H. Hahn. 2021. 'Predictors of Nonseroconversion after SARS-CoV-2 Infection', Emerg Infect Dis, 27: 2454-58. Article
Mast, F. D., P. C. Fridy, N. E. Ketaren, J. Wang, E. Y. Jacobs, J. P. Olivier, T. Sanyal, K. R. Molloy, F. Schmidt, M. Rutkowska, Y. Weisblum, L. M. Rich, E. R. Vanderwall, N. Dambrauskas, V. Vigdorovich, S. Keegan, J. B. Jiler, M. E. Stein, P. D. B. Olinares, L. Herlands, T. Hatziioannou, D. N. Sather, J. S. Debley, D. Fenyo, A. Sali, P. D. Bieniasz, J. D. Aitchison, B. T. Chait, and M. P. Rout. 2021. 'Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape', Elife, 10. Article
McDonald, L., H. Wise, F. Muecksch, D. Poston, S. Mavin, K. Templeton, E. Furrie, C. Richardson, J. McGuire, L. Jarvis, K. Malloy, A. McAuley, N. Palmateer, E. Dickson, T. Hatziioannou, P. Bieniasz, and S. Jenks. 2021. 'Comparison of SARS-CoV-2 serological assays for use in epidemiological surveillance in Scotland', J Clin Virol Plus, 1: 100028. Article
Muecksch, F., Y. Weisblum, C. O. Barnes, F. Schmidt, D. Schaefer-Babajew, Z. Wang, C. Lorenzi JC, A. I. Flyak, A. T. DeLaitsch, K. E. Huey-Tubman, S. Hou, C. A. Schiffer, C. Gaebler, J. Da Silva, D. Poston, S. Finkin, A. Cho, M. Cipolla, T. Y. Oliveira, K. G. Millard, V. Ramos, A. Gazumyan, M. Rutkowska, M. Caskey, M. C. Nussenzweig, P. J. Bjorkman, T. Hatziioannou, and P. D. Bieniasz. 2021. 'Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations', Immunity, 54: 1853-68 e7. Article
Poston, D., T. Zang, and P. Bieniasz. 2021. 'Derivation and characterization of an HIV-1 mutant that rescues IP(6) binding deficiency', Retrovirology, 18: 25. Article
Ricardo-Lax, I., J. M. Luna, T. T. N. Thao, J. Le Pen, Y. Yu, H. H. Hoffmann, W. M. Schneider, B. S. Razooky, J. Fernandez-Martinez, F. Schmidt, Y. Weisblum, B. S. Trueb, I. Berenguer Veiga, K. Schmied, N. Ebert, E. Michailidis, A. Peace, F. J. Sanchez-Rivera, S. W. Lowe, M. P. Rout, T. Hatziioannou, P. D. Bieniasz, J. T. Poirier, M. R. MacDonald, V. Thiel, and C. M. Rice. 2021. 'Replication and single-cycle delivery of SARS-CoV-2 replicons', Science, 374: 1099-106. Article
Scheid, J. F., C. O. Barnes, B. Eraslan, A. Hudak, J. R. Keeffe, L. A. Cosimi, E. M. Brown, F. Muecksch, Y. Weisblum, S. Zhang, T. Delorey, A. E. Woolley, F. Ghantous, S. M. Park, D. Phillips, B. Tusi, K. E. Huey-Tubman, A. A. Cohen, P. N. P. Gnanapragasam, K. Rzasa, T. Hatziioannou, M. A. Durney, X. Gu, T. Tada, N. R. Landau, A. P. West, Jr., O. Rozenblatt-Rosen, M. S. Seaman, L. R. Baden, D. B. Graham, J. Deguine, P. D. Bieniasz, A. Regev, D. Hung, P. J. Bjorkman, and R. J. Xavier. 2021. 'B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV', Cell, 184: 3205-21 e24. Article
Schmidt, F., Y. Weisblum, M. Rutkowska, D. Poston, J. DaSilva, F. Zhang, E. Bednarski, A. Cho, D. J. Schaefer-Babajew, C. Gaebler, M. Caskey, M. C. Nussenzweig, T. Hatziioannou, and P. D. Bieniasz. 2021. 'High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape', Nature, 600: 512-16. Article
Starzer, A. M., A. S. Berghoff, R. Hamacher, E. Tomasich, K. Feldmann, T. Hatziioannou, S. Traint, W. Lamm, I. M. Noebauer-Huhmann, J. Furtner, L. Mullauer, G. Amann, S. Bauer, H. U. Schildhaus, M. Preusser, G. Heller, and T. Brodowicz. 2021. 'Tumor DNA methylation profiles correlate with response to anti-PD-1 immune checkpoint inhibitor monotherapy in sarcoma patients', J Immunother Cancer, 9. Article
Van Rompay, K. K. A., K. J. Olstad, R. L. Sammak, J. Dutra, J. K. Watanabe, J. L. Usachenko, R. Immareddy, A. Verma, Y. Shaan Lakshmanappa, B. A. Schmidt, J. W. Roh, S. R. Elizaldi, A. M. Allen, F. Muecksch, J. C. C. Lorenzi, S. Lockwood, R. E. Pollard, J. L. Yee, P. B. Nham, A. Ardeshir, J. D. Deere, J. Patterson, Q. Dang, T. Hatziioannou, P. D. Bieniasz, S. S. Iyer, D. J. Hartigan-O'Connor, M. C. Nussenzweig, and J. R. Reader. 2021. 'Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques', PLoS Pathog, 17: e1009688. Article
Wang, Z., J. C. C. Lorenzi, F. Muecksch, S. Finkin, C. Viant, C. Gaebler, M. Cipolla, H. H. Hoffmann, T. Y. Oliveira, D. A. Oren, V. Ramos, L. Nogueira, E. Michailidis, D. F. Robbiani, A. Gazumyan, C. M. Rice, T. Hatziioannou, P. D. Bieniasz, M. Caskey, and M. C. Nussenzweig. 2021. 'Enhanced SARS-CoV-2 neutralization by dimeric IgA', Sci Transl Med, 13. Article
Wang, Z., F. Muecksch, D. Schaefer-Babajew, S. Finkin, C. Viant, C. Gaebler, H. H. Hoffmann, C. O. Barnes, M. Cipolla, V. Ramos, T. Y. Oliveira, A. Cho, F. Schmidt, J. Da Silva, E. Bednarski, L. Aguado, J. Yee, M. Daga, M. Turroja, K. G. Millard, M. Jankovic, A. Gazumyan, Z. Zhao, C. M. Rice, P. D. Bieniasz, M. Caskey, T. Hatziioannou, and M. C. Nussenzweig. 2021. 'Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection', Nature, 595: 426-31. Article
Xu, J., K. Xu, S. Jung, A. Conte, J. Lieberman, F. Muecksch, J. C. C. Lorenzi, S. Park, F. Schmidt, Z. Wang, Y. Huang, Y. Luo, M. S. Nair, P. Wang, J. E. Schulz, L. Tessarollo, T. Bylund, G. Y. Chuang, A. S. Olia, T. Stephens, I. T. Teng, Y. Tsybovsky, T. Zhou, V. Munster, D. D. Ho, T. Hatziioannou, P. D. Bieniasz, M. C. Nussenzweig, P. D. Kwong, and R. Casellas. 2021. 'Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants', Nature, 595: 278-82. Article
2020
Barnes, C. O., A. P. West, Jr., K. E. Huey-Tubman, M. A. G. Hoffmann, N. G. Sharaf, P. R. Hoffman, N. Koranda, H. B. Gristick, C. Gaebler, F. Muecksch, J. C. C. Lorenzi, S. Finkin, T. Hagglof, A. Hurley, K. G. Millard, Y. Weisblum, F. Schmidt, T. Hatziioannou, P. D. Bieniasz, M. Caskey, D. F. Robbiani, M. C. Nussenzweig, and P. J. Bjorkman. 2020. 'Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies', Cell, 182: 828-42 e16. Article
Jia, M., R. A. Liberatore, Y. Guo, K. W. Chan, R. Pan, H. Lu, E. Waltari, E. Mittler, K. Chandran, A. Finzi, D. E. Kaufmann, M. S. Seaman, D. D. Ho, L. Shapiro, Z. Sheng, X. P. Kong, P. D. Bieniasz, and X. Wu. 2020. 'VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA', Cell Host Microbe, 27: 963-75 e5. Article
Kane, M., V. Mele, R. A. Liberatore, and P. D. Bieniasz. 2020. 'Inhibition of spumavirus gene expression by PHF11', PLoS Pathog, 16: e1008644. Article
Luchsinger, L. L., B. P. Ransegnola, D. K. Jin, F. Muecksch, Y. Weisblum, W. Bao, P. J. George, M. Rodriguez, N. Tricoche, F. Schmidt, C. Gao, S. Jawahar, M. Pal, E. Schnall, H. Zhang, D. Strauss, K. Yazdanbakhsh, C. D. Hillyer, P. D. Bieniasz, and T. Hatziioannou. 2020. 'Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID-19 Patients', J Clin Microbiol, 58. Article
Robbiani, D. F., C. Gaebler, F. Muecksch, J. C. C. Lorenzi, Z. Wang, A. Cho, M. Agudelo, C. O. Barnes, A. Gazumyan, S. Finkin, T. Hagglof, T. Y. Oliveira, C. Viant, A. Hurley, H. H. Hoffmann, K. G. Millard, R. G. Kost, M. Cipolla, K. Gordon, F. Bianchini, S. T. Chen, V. Ramos, R. Patel, J. Dizon, I. Shimeliovich, P. Mendoza, H. Hartweger, L. Nogueira, M. Pack, J. Horowitz, F. Schmidt, Y. Weisblum, E. Michailidis, A. W. Ashbrook, E. Waltari, J. E. Pak, K. E. Huey-Tubman, N. Koranda, P. R. Hoffman, A. P. West, Jr., C. M. Rice, T. Hatziioannou, P. J. Bjorkman, P. D. Bieniasz, M. Caskey, and M. C. Nussenzweig. 2020. 'Convergent antibody responses to SARS-CoV-2 in convalescent individuals', Nature, 584: 437-42. Article
Tomezsko, P. J., V. D. A. Corbin, P. Gupta, H. Swaminathan, M. Glasgow, S. Persad, M. D. Edwards, L. McIntosh, A. T. Papenfuss, A. Emery, R. Swanstrom, T. Zang, T. C. T. Lan, P. Bieniasz, D. R. Kuritzkes, A. Tsibris, and S. Rouskin. 2020a. 'Author Correction: Determination of RNA structural diversity and its role in HIV-1 RNA splicing', Nature, 582: 438-42. Article
Weisblum, Y., F. Schmidt, F. Zhang, J. DaSilva, D. Poston, J. C. Lorenzi, F. Muecksch, M. Rutkowska, H. H. Hoffmann, E. Michailidis, C. Gaebler, M. Agudelo, A. Cho, Z. Wang, A. Gazumyan, M. Cipolla, L. Luchsinger, C. D. Hillyer, M. Caskey, D. F. Robbiani, C. M. Rice, M. C. Nussenzweig, T. Hatziioannou, and P. D. Bieniasz. 2020. 'Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants', Elife, 9. Article
Zhang, F., and P. D. Bieniasz. 2020. 'HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137', Elife, 9. Article
2019
Bohn, J. A., J. DaSilva, S. Kharytonchyk, M. Mercedes, J. Vosters, A. Telesnitsky, T. Hatziioannou, and J. L. Smith. 2019. 'Flexibility in Nucleic Acid Binding Is Central to APOBEC3H Antiviral Activity', J Virol, 93. Article
Kueck, T., L. M. Bloyet, E. Cassella, T. Zang, F. Schmidt, V. Brusic, G. Tekes, O. Pornillos, S. P. J. Whelan, and P. D. Bieniasz. 2019. 'Vesicular Stomatitis Virus Transcription Is Inhibited by TRIM69 in the Interferon-Induced Antiviral State', J Virol, 93. Article
Kutluay, S. B., A. Emery, S. R. Penumutchu, D. Townsend, K. Tenneti, M. K. Madison, A. M. Stukenbroeker, C. Powell, D. Jannain, B. S. Tolbert, R. I. Swanstrom, and P. D. Bieniasz. 2019. 'Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing', J Virol, 93. Article
Liberatore, R. A., E. J. Mastrocola, E. Cassella, F. Schmidt, J. R. Willen, D. Voronin, T. M. Zang, T. Hatziioannou, and P. D. Bieniasz. 2019. 'Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection', Elife, 8. Article
Meagher, J. L., M. Takata, D. Goncalves-Carneiro, S. C. Keane, A. Rebendenne, H. Ong, V. K. Orr, M. R. MacDonald, J. A. Stuckey, P. D. Bieniasz, and J. L. Smith. 2019. 'Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences', Proc Natl Acad Sci U S A, 116: 24303-09. Article
O'Brien, S. P., A. E. Swanstrom, A. Pegu, S. Y. Ko, T. T. Immonen, G. Q. Del Prete, C. M. Fennessey, J. Gorman, K. E. Foulds, S. D. Schmidt, N. Doria-Rose, C. Williamson, T. Hatziioannou, P. D. Bieniasz, H. Li, G. M. Shaw, J. R. Mascola, R. A. Koup, P. D. Kwong, J. D. Lifson, M. Roederer, and B. F. Keele. 2019. 'Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes', PLoS Pathog, 15: e1007632. Article
Schmidt, F., B. F. Keele, G. Q. Del Prete, D. Voronin, C. M. Fennessey, S. Soll, M. Kane, A. Raymond, R. J. Gifford, V. KewalRamani, J. D. Lifson, P. D. Bieniasz, and T. Hatziioannou. 2019. 'Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host', Proc Natl Acad Sci U S A, 116: 10504-09. Article
Swanstrom, A. E., A. Jacques, G. Q. Del Prete, P. Bieniasz, T. Hatziioannou, R. Gorelick, and J. D. Lifson. 2019. 'Short Communication: Ultrasensitive Immunoassay for Assessing Residual Simian-Tropic HIV in Nonhuman Primate Models of AIDS', AIDS Res Hum Retroviruses, 35: 473-76. Article
2018
Bieniasz, P. D. 2018. 'A multimodal antiretroviral protein', Nat Microbiol, 3: 122-23. Article
Bieniasz, P. D., and S. B. Kutluay. 2018. 'CLIP-related methodologies and their application to retrovirology', Retrovirology, 15: 35. Article
Bieniasz, P., and A. Telesnitsky. 2018. 'Multiple, Switchable Protein:RNA Interactions Regulate Human Immunodeficiency Virus Type 1 Assembly', Annu Rev Virol, 5: 165-83. Article
Blanco-Melo, D., R. J. Gifford, and P. D. Bieniasz. 2018. 'Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L', Retrovirology, 15: 34. Article
Feng, J., A. Wickenhagen, M. L. Turnbull, V. V. Rezelj, F. Kreher, N. L. Tilston-Lunel, G. S. Slack, B. Brennan, E. Koudriakova, A. E. Shaw, S. J. Rihn, C. M. Rice, P. D. Bieniasz, R. M. Elliott, X. Shi, and S. J. Wilson. 2018. 'Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20', J Virol, 92. Article
Kane, M., S. V. Rebensburg, M. A. Takata, T. M. Zang, M. Yamashita, M. Kvaratskhelia, and P. D. Bieniasz. 2018. 'Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2', Elife, 7. Article
Kueck, T., E. Cassella, J. Holler, B. Kim, and P. D. Bieniasz. 2018. 'The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression', Elife, 7. Article
Takata, M. A., S. J. Soll, A. Emery, D. Blanco-Melo, R. Swanstrom, and P. D. Bieniasz. 2018. 'Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication', PLoS Pathog, 14: e1006824. Article
2017
Bieniasz, P. 2017. 'Repurposing a Bacterial Immune System to Discover Antiviral Targets', N Engl J Med, 376: 1290-91. Article
Blanco-Melo, D., R. J. Gifford, and P. D. Bieniasz. 2017. 'Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors', Elife, 6. Article
Bohn, J. A., K. Thummar, A. York, A. Raymond, W. C. Brown, P. D. Bieniasz, T. Hatziioannou, and J. L. Smith. 2017. 'APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA', Nat Commun, 8: 1021. Article
Del Prete, G. Q., B. F. Keele, J. Fode, K. Thummar, A. E. Swanstrom, A. Rodriguez, A. Raymond, J. D. Estes, C. C. LaBranche, D. C. Montefiori, V. N. KewalRamani, J. D. Lifson, P. D. Bieniasz, and T. Hatziioannou. 2017. 'A single gp120 residue can affect HIV-1 tropism in macaques', PLoS Pathog, 13: e1006572. Article
Liberatore, R. A., E. J. Mastrocola, C. Powell, and P. D. Bieniasz. 2017. 'Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus Pathogenesis', J Virol, 91. Article
Takata, M. A., D. Goncalves-Carneiro, T. M. Zang, S. J. Soll, A. York, D. Blanco-Melo, and P. D. Bieniasz. 2017. 'CG dinucleotide suppression enables antiviral defence targeting non-self RNA', Nature, 550: 124-27. Article